【摘要】 目的：探讨应用恩丹西酮、氟哌利多预防术后恶心、呕吐的效果。方法：按美国麻醉协会分级（ＡＳＡ）Ⅰ～Ⅱ级择期全子宫切除６０例，随机分为三组：Ａ组，静脉注射１０ｍｌ生理盐水；Ｂ组，静脉注射恩丹西酮４ｍｌ和生理盐水１０ｍｌ；Ｃ组，静脉注射氟哌利多２．５ｍｇ和生理盐水１０ｍｌ，观察各组术后２４ｈ内恶心的程度和呕吐次数，同时记录副作用。结果：Ａ组患者恶心、呕吐发生率均高于Ｂ组和Ｃ组（Ｐ＜０．０１），而Ｂ组和Ｃ组差异无显著性（Ｐ＞０．０５）。三组均无明显的副作用。结论：恩丹西酮和氟哌利多对全子宫切除术后均有良好的预防恶心、呕吐的作用更多还原

【Abstract】 Objective:To evaluate the efficacy of ondansetron and droperidol for prophylactic treatment of postoperative nausea and vomiting.Methods:Sixty patients under anesthesia ASA Ⅰ～Ⅱ,for total hysterectomy were divided at random into three groups:Group A received Ⅳ normal saline 10 ml ,group B received Ⅳ ondansetron 4 mg and normal saline 10 ml,group C received Ⅳ droperidol 2.5 mg and normal saline 10 ml.Nausea vomiting and other adverse effects within 24 hours after operation were recorded.Results:The incidence of nausea and vomiting in group A is significantly higher than that in group B and group C( P <0.01),but the difference between B and C was not significant( P >0.05).No patient in these three groups showed severe adverse effect.Conclusions:Ondansetron and droperidol can be used in prophylactic treatment of nausea and vomiting in total hysterectomy under epidural anesthesia.更多还原