【作者】 代锟； 张莉莉； 夏语； 孙富强； 任哲； 卢庚辰； 程斌；

【Author】 Dai Kun;ZhangLili;XiaYu;SunFuqiang;RenZhe;LuGengchen;ChengBin;Shandong University of Traditional Chinese Medicine;Jinan Central Hospital Affiliated to Shandong First Medical University;The Affiliated Hospital of Shandong University of Traditional Chinese Medicine;

【机构】 山东中医药大学； 山东第一医科大学附属济南中心医院； 山东中医药大学附属医院；

【摘要】 目的观察针刺联合血管内介入治疗缺血性脑卒中患者的临床疗效。方法将60例缺血性脑卒中(IS)患者随机分为对照组和试验组,每组各30例。对照组给予血管内介入治疗及术后常规治疗,试验组在对照组基础上加用针刺治疗,疗程为2周。分别评估2组患者治疗前、治疗2周后的美国国立卫生研究院卒中量表(NIHSS)评分、改良Barthel(BI)评分和改良Rankin量表(mRs)评分的变化情况,并评价2组患者的临床疗效和安全性。结果 (1)治疗2周后,试验组的有效率为86.7%,对照组为66.7%。试验组的疗效明显优于对照组,差异有统计学意义(P<0.05)。(2)治疗2周后,2组患者的NIHSS均较治疗前明显降低(P<0.01),且试验组的评分明显低于对照组,差异有统计学意义(P<0.05)。(3)治疗2周后,2组患者的mRs评分较治疗前明显降低,BI评分较治疗前明显升高(P<0.01),且试验组对mRs评分的降低作用和BI评分的升高作用均明显优于对照组,差异均有统计学意义(P<0.05)。(4)治疗后,试验组的不良事件发生率为6.6%,对照组为13.3%,试验组安全性高于对照组,差异无统计学意义(P>0.05)。结论缺血性脑卒中介入术后患者采用针刺治疗疗效显著,安全性高,能有效改善神经功能,减轻症状,提高生活能力,优于单纯血管内介入治疗。更多还原

【Abstract】 Objective:To observe the clinical efficacy of acupuncture combined with endovascular intervention in the treatment of patients with ischemic stroke.Methods:A total of 60 patients with ischemic stroke(IS) were randomly divided into a control group and an experimental group,with 30 cases in each group.The control group received endovascular intervention and routine postoperative treatment,while the experimental group received additional acupuncture treatment on the basis of the control group,with a treatment course of 2 weeks.The changes in the National Institutes of Health Stroke Scale(NIHSS) score,modified Barthel(BI) score,and modified Rankin scale(mRS) score before treatment and after 2 weeks of treatment in the two groups were evaluated,and the clinical efficacy and safety of the two groups were assessed.Results:(1) After 2 weeks of treatment,the effective rate of the experimental group was 86.7%,and that of the control group was 66.7%.The efficacy of the experimental group was significantly better than that of the control group,with a statistically significant difference(P<0.05).(2) After 2weeks of treatment,the NIHSS scores of both groups were significantly lower than before treatment(P<0.01),and the score of the experimental group was significantly lower than that of the control group,with a statistically significant difference(P<0.05).(3) After 2 weeks of treatment,the m RS scores of both groups were significantly lower than before treatment,and the BI scores were significantly higher than before treatment(P<0.01),and the experimental group’s effect on reducing m RS scores and increasing BI scores was significantly better than that of the control group,with statistically significant differences(P<0.05).(4) After treatment,the adverse event rate of the experimental group was 6.6%,and that of the control group was 13.3%.The safety of the experimental group was higher than that of the control group,but the difference was not statistically significant(P>0.05).Conclusion:Acupuncture treatment after endovascular intervention in patients with ischemic stroke has significant efficacy and high safety,which can effectively improve neurological function,alleviate symptoms,and enhance the ability to live,and is superior to simple endovascular intervention treatment.更多还原