【作者】 卢映君； 张维森； 朱彤； 靳雅丽； 潘静； 江朝强；

【Author】 LU Yingjun;ZHANG Weisen;ZHU Tong;JIN Yali;PAN Jing;JIANG Chaoqiang;Department of Occupational Health Management, Guangzhou Twelfth People’s Hospital;

【机构】 广州市第十二人民医院职业卫生管理科； 广州市第十二人民医院分子流行病学研究室； 广州市第十二人民医院科教信息科；

【摘要】 目的:比较综合评分的社会经济状况(CS-SES)和其代表性指标与老年抑郁症状(GDS)的相关性,以探讨更合理的社会经济状况评价指标。方法:基于广州生物库队列基线调查数据,选择其中完成老年抑郁量表(GDS-15)测试者为研究对象,采用多因素logisitic回归模型,分析CS-SES及其代表性指标(文化程度、职业、家庭年收入)与GDS(GDS得分≥5分)的关联和代表性指标间的交互作用。结果:本研究共纳入9 739人,平均年龄60.2±7.8岁,GDS患病率14.5%。调整性别、年龄、婚姻、吸烟、饮酒、体力活动、饮食习惯、自评健康和共病后,CS-SES、文化程度、职业、家庭年收入均与GDS独立相关,GDS患病风险随CS-SES和文化程度的降低而上升(P趋势<0.001)。GDS患病风险比:CS-SES中和低者与CS-SES高者比,分别增加47%(95%CI:25～74%)和112%(95%CI:81～150%);初中、小学或以下文化与高中或以上文化比,分别增加22%(95%CI:4～44%)和43%(95%CI:21～69%);手工作业或其他职业与非手工作业比,增加33%(95%CI:11～59%),家庭年收入不足3万元或不确定与达到或超过3万元者比,增加45%(95%CI:27～65%)。文化程度、家庭年收入和职业与抑郁症状的相关不存在交互作用。结论:综合评分的社会经济状况与老年抑郁症状的相关性优于其代表性指标。更多还原

【Abstract】 Objective To compare the correlation of comprehensive scoring of socioeconomic status(CS-SES) and geriatric depressive syndromes(GDS) to explore more reasonable indicators of socioeconomic status. Methods Based on the baseline survey data of the Guangzhou Biobank cohort, the subjects completing the geriatric depression scale(GDS-15) were selected as subjects of the study, and the multivariate logisitic regression model was used to analyze the association between CS-SES and its representative indicators(degree of education, occupation, annual representative indicators each other for the association. Results A total of 9 739 individuals were included, with a mean age of 60.2±7.8 years, and the prevalence of GDS was 14.5%. After adjusting for gender, age, marriage, smoking, alcohol drinking, physical activity, diet habits, self-rated health and comorbidities, CS-SES, degree of education, occupation, and annual household income were all independently associated with GDS, The risk of GDS increased with decreasing CS-SES and degree of education(P trend <0.001); Compared with the high level of CS-SES, the risks of GDS in those with middle and low level of CS-SES increased by 47%(95%CI: 25-74%) and 112%(95%CI: 81-150%), respectively. Compared to a high school or above education, The risk of GDS in those with middle school and primary school or below increased by 22%(95%CI: 4-44%) and 43%(95%CI: 21-69%), respectively. Compared to the non-manual occupation, The risk of GDS in those with manual occupation increased by 33%(95%CI: 11 to 59%), Compared with the annual family income reaching or exceeding 30,000 Chinese yuan, The risk of GDS in those with annual family income below 30000 Chinese yuan increased 45%(95%CI: 27-65%). There was no interaction between degree of education, annual household income and occupation and depression Conclusion Comprehensive score of socioeconomic status was better associated with geriatric depressive syndromes than its representative index.更多还原