【作者】 罗熙； 申永辉； 孙丽君； 齐雪君； 吴满花； 车先伟； 李红；

【Author】 Xi Luo;Yonghui Shen;Lijun Sun;Xuejun Qi;Manhua Wu;Xianwei Che;Hong Li;School of Nursing,Hangzhou Medical College;Hangzhou Seventh People’s Hospital;Centre for Cognition and Brain Disorders,Hangzhou Normal University;School of Psychology,South China Normal University;

【机构】 杭州医学院护理学院； 杭州市第七人民医院； 杭州师范大学认知与脑疾病中心； 华南师范大学心理学院；

【摘要】 广泛性焦虑障碍(Generalized anxiety disorder,GAD)是最普遍的、也是最难成功治疗的焦虑症。越来越多的证据表明自悯在焦虑症治疗中有重要作用,但是目前研究没有将自悯训练用于治疗GAD。本研究旨在考察两周八次的自悯训练对GAD的疗效,并与经典的正念治疗进行直接比较。75名GAD患者被分配到自悯训练组(n=25)、正念训练组(n=25)、常规治疗组(n=25)(ClinicalTrials注册ID:ChiCTR2100053374),其中自悯训练组和正念训练组除了接受包含药物使用的常规治疗之外,还分别接受自悯或正念训练。主要结果变量包括汉密尔顿焦虑量表和宾州担忧问卷,并在干预前、干预后和干预后三个月分别施测。次要结果包括汉密尔顿抑郁量表、匹兹堡睡眠质量指数、自悯量表和多伦多正念量表。根据意向性分析原则(Intention-to-treat Analysis,ITT)对改变量进行了方差分析,并基于此建立了中介模型。结果显示,自悯训练组和正念训练组都能有效降低GAD患者的焦虑和抑郁,并且比常规治疗组起效更快。三组的担忧变化无差异。中介分析显示,自悯通过降低焦虑来改善睡眠质量。我们结果表明自悯训练组和正念训练组都能有效降低GAD患者的临床症状,但自悯训练的愉悦体验和接受程度更高,而且自悯训练通过降低焦虑间接地改善GAD患者的睡眠质量。研究结果表明自悯训练对GAD临床治疗具有巨大的潜力,有望成为新的辅助心理治疗工具。更多还原

【Abstract】 Generalized anxiety disorder(GAD) is the most common anxiety disorder and very difficult to treat successfully.Many studies have shown the potential of self-compassion in reducing anxiety symptoms,but no studies have applied self-compassion training to the treatment of GAD.The aim of this study was to examine the effect of a two-week self-compassion training including eight sessions for GAD,in direct comparison with classic mindfulness-based treatment.75 GAD patients were assigned to self-compassion training group(n=25),mindfulness training group(n=25),treat-as-usal group(n=25)(ClinicalTrials registration ID:ChiCTR2100053374),in which self-compassion training group and mindfulness training groups received either self-compassion or mindfulness training respectively,in addition to treat-as-usal i.e.,medication use.Primary outcomes included the Hamilton Anxiety Rating Scale and the Penn State Worry Questionnaire,which were administered at pre-intervention,post-intervention,and three months after the intervention.Secondary outcomes included the Hamilton Depression Rating Scale,the Pittsburgh Sleep Quality Index,the Self-Compassion Scale,and the Toronto Mindfulness Scale.According to the principle of intention analysis(Intention-to-treat Analysis,ITT),analysis was carried out on the variables of change,and a mediation model was established based on this.Results showed that both the self-compassion training and mindfulness training group effectively reduced anxiety and depression in patients with GAD,and the effect came faster than the treat-as-usal group.There was no difference in change in worry among the three groups.Mediation analysis revealed that self-compassion improves sleep quality by reducing anxiety.Our results show that both the self-compassion training group and the mindfulness training group can reduce the clinical symptoms of patients with GAD,but the pleasure and acceptability of self-compassion training are higher,and self-compassion training can improve the sleep quality of GAD patients by reducing anxiety.These findings suggest that self-compassion training has great potential for the treatment of GAD and is expected to be a promising psychotherapy tool.更多还原