【作者】 陈田； 汤杨； 佘媛媛； 李竹； 崔文广； 孙广文； 陈健； 周利红；

【Author】 CHEN Tian;TANG Yang;SHE Yuanyuan;LI Zhu;CUI Wenguang;SUN Guangwen;CHEN Jian;ZHOU Li-hong;Shanghai Municipal Center for Disease Control and Prevention;

【机构】 上海市疾病预防控制中心公共服务与健康安全评价所； 国家药品监督管理局化妆品监测评价重点实验室；

【摘要】 目的调查上海市女性消费人群对常用驻留类化妆品的使用情况和使用习惯,为化妆品安全评估工作提供关键暴露参数。方法本研究为横断面研究。2021年8月至12月期间抽取上海市女性化妆品消费者进行问卷调查,记录14天调查期内护肤水、精华液、护肤乳、面霜、眼霜、防晒霜等六类产品的使用情况,并使用差量法计重。结果本研究共纳入309例有效样本量。每款产品平均每日和每次使用量第90百分位数(P90)分别是:护肤水2.47g和1.61g、精华液0.84g和0.69g、乳液1.62g和1.03g、面霜0.89g和0.80g、眼霜0.23g和0.21g、防晒霜0.68g和0.97g,总体低于国外人群。此外,年龄<45岁者防晒霜平均每次使用量更高;不同肤质、敏感性皮肤与否对选定化妆品的使用量没有影响。结论本土人群的化妆品暴露参数与国外人群不同,为保证化妆品安全评估的准确性,建议参考本土人群的暴露数据。更多还原

【Abstract】 OBJECTIVE To investigate the actual use of skin care products commonly used by female consumers in Shanghai, and provide key exposure parameters for the safety assessment of cosmetics in China. METHODS From August to December 2021, female cosmetic consumers in Shanghai were selected to conduct a questionnaire survey, and then the usage of 6 types of products including skin lotion, essence, skin lotion, face cream, eye cream, and sunscreen during the 14-day survey period was recorded, and the total use of different products was obtained by differential weighing. RESULTS A total of 309 samples were included in this study. The 90th percentile(P90) of the mean amount applied per day and per application of each product were 2.47g and 1.61g for skin lotion, 0.84g and 0.69g for serum, 1.62g and 1.03g for lotion, 0.89g and 0.80g for cream, 0.23g and 0.21g for eye cream, 0.68g and 0.97g for sunscreen, which were generally lower than data from European, American and Japanese populations. In addition, the average amount of sunscreen used per time was higher in those aged <45 years; different skin types, sensitive skin or not had no effect on the amount of these skin care products. CONCLUSION The exposure to skin care products of the local population is different from the data from the foreign population. It is recommended to use these data of the local population to carry out cosmetic safety assessment to improve the accuracy.更多还原