Synthesis, Surface Activity and Antimicrobial Efficacy of Diaryliodonium Salts-Derived Amphiphiles

【作者】 黄蒙恩； Shujia Xu； Xunshen Wu； 赵敏； 王利民；

【Author】 Mengen Huang;Shujia Xu;Xunshen Wu;Min Zhao;Limin Wang;Key Laboratory for Advanced Materials,Institute of Fine Chemicals,School of Chemistry and Molecular Engineering,East China University of Science and Technology;School of Chemistry and Molecular Engineering,East China University of Science and Technology;Key Laboratory of Organofluorine Chemistry,Shanghai Institute of Organic Chemistry,The Chinese Academy of Sciences;

【机构】 Key Laboratory for Advanced Materials,Institute of Fine Chemicals,School of Chemistry and Molecular Engineering,East China University of Science and Technology； School of Chemistry and Molecular Engineering,East China University of Science and Technology； Key Laboratory of Organofluorine Chemistry,Shanghai Institute of Organic Chemistry,The Chinese Academy of Sciences；

【摘要】 <正>Two sets of 19 diaryliodonium salts were synthesized and their tensiometric property as well as antimicrobial ability against Gram-positive Bacillus cereus were tested. All 19 salts dissolve well in water solution. Diaryliodonium salts bearing OTs as counter ion exhibited lower CMC values than its OTf counterpart. The surfaceactive properties of diaryliodonium salt could be well enhanced by introducing fluorine onto its molecular structure. Antibacterial measurement results suggested that all 19 diaryliodonium salts exhibited great bactericidal efficacy within the first 4 hours, indicating great short-term antimicrobial efficacy and implying possible antiseptic mechanism through oxidizing. Fluorinated diaryliodonium salts designed in this work showed equivalent antiseptic efficacy.更多还原