【作者】 姚萌； 苏帝翰； 邵正中；

【Author】 Meng Yao;Dihan Su;Zhengzhong Shao;State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science and Laboratory of Advanced Materials, Fudan University;

【机构】 聚合物分子工程国家重点实验室复旦大学高分子科学系和先进材料实验室；

【摘要】 <正>众所周知,溶液中的桑蚕丝蛋白能够形成以β-折叠为主的物理交联点(区域),进而产生凝胶网络,这是个热力学控制的过程。但由于力学性能较差,普通的蚕丝蛋白水凝胶材料在应用上受到了较大的限制。尽管有研究报道称,采用辣根过氧化物酶化学交联得到的丝蛋白水凝胶具有很好的弹性,但其模量依然不高(储能模量在0.1～10 kPa之间)[1];同时,此类仅利用丝蛋白中酪氨酸残基起交联点作用的水凝胶结构不稳定,通常在保存时会出现凝胶至溶液(溶胶)的转变。更多还原

【Abstract】 In this work, the regenerated silk fibroin（RSF, from Bombyx mori） hydrogel with both excellent strength and elasticity was prepared by inducing the conformation transition from random coil to β-sheet in a restricted RSF network pre-cross-linked by HRP/H₂ O₂. Such "dual-networked" hydrogels, show around 100 % elongation, as well as the compressive modulus and tensile modulus up to 3.0 MPa and 2.5 MPa respectively, which are much higher than those of physically cross-linked natural polymer hydrogels. After the involvement of ionic liquid, a RSF/EMImAc/H₂ O gel with tunable strength and flexibility, favorable conductivity, and remarkable air-stability was also developed.更多还原