【作者】 谭守勇； 龚芳； 刘国标； 黎燕琼；

【Author】 Tan Shouyong;Gong Fang;Liu Guobiao;Li Yanqiong;State Key Laboratory of Respiratory Diseases,Department of Pulmonary Tuberculosis,Guangzhou Chest Hospital;

【机构】 广州市胸科医院；

【摘要】 目的了解结核专科门诊初治肺结核并肺部感染现状,探讨肺结核并肺部感染患者的临床特点。方法采用回顾性分析的方法。对2015年1月至2016年6月在广州市某区结核病防治所就诊初治菌阳肺结核临床资料齐全的506例患者进行分析。结果 506例肺结核患者中并发肺部感染200例(39.5%);在98例老年肺结核患者中,并肺部感染者49例(50.0%)(χ~2=6.583,P=0.037)。在肺结核并肺部感染患者(感染组)中,伴有咳嗽或咳痰症状166例(83.00%),略高于非感染组(76.47%)(χ~2=3.510,P=0.319);感染组患者肺部累及病灶>3肺野98例(49.00%)明显高于非感染组31.70%(χ~2=6.965,P=0.008);感染组患者中,肺结核并空洞者85例(42.50%)明显高于非感染组26.80%(χ~2=13.487,P=0.000)。结论在初治菌阳肺结核患者中相当一部分患者就诊时并肺部感染,以老年患者多见;其次,并肺部感染患者,常伴有咳嗽或咳痰症状,病灶较广泛,常伴有空洞形成。因此,临床上对初诊肺结核患者注意排除并肺部感染。更多还原

【Abstract】 objective:To understand the present situation for the pulmonary tuberculosis with pulmonary infection(PTB&PIN),and to explore the patients’ clinical characteristics for PTB&PIN in Tuberculosis Clinic.Methods:A retrospective analysis was carried out on 506 patients with pulmonary tuberculosis(PTB) for the complete clinical data from January 2015 to June 2016 in a tuberculosis prevention and treatment center in a district of Guangzhou.Results:Of the 506 patients with PTB,200 cases were complicated with pulmonary infection(PIN).There were 98 patients aged with over 60 years,and out of 49 patients(50.0%) cases with PIN(χ~2=6.583,P=0.037).In the patients with PTB&PIN(infection group),166 cases(83.00) with cough or expectoration symptoms were same as that in the patients with PTB(noninfection group)(76.47%)(χ~2=3.510,P=0.319).Thepatients with the lung involvementover 3 lesions in the infection group(49.00%) were significantly higher than that in the non-infected group(31.70%)(χ~2=6.965,P=0.008),while in the infected group,85 cases(42.50%) with cavities in the focus were significantly higher than that in the non-infected group(26.80%)(χ~2=13.487,P=0.000).Conclusion:In the first treatment of the patients with bacterial positive pulmonary tuberculosis,a large number of patients with pulmonary infection,mainly in the elderly.Secondly,the patients with pulmonary infection are often accompanied with cough or expectoration symptoms,with a wide range of lesions,often accompanied by cavity formation.Clinically,the patients with newly diagnosed pulmonary tuberculosis should be excluded from pulmonary infection.更多还原