【作者】 韦寿莲； 高秀超； 郭秀燕； 姚夙； 汪洪武；

【Author】 Shoulian Wei;Xiuchao Gao;Xiuyan Guo;Su Yao;Hongwu Wang;Faculty of Chemistry and Chemical Engineering, Zhaoqing University;

【机构】 肇庆学院；

【摘要】 铁掺杂大孔碳复合材料具有大量连通的孔穴结构,表面积大,电子传递速度快,具有良好的催化性能。羟丙基-β-环糊精特有的"锥筒"结构能与客体分子形成复合物,生物相容性好,因此广泛应用于食品、农业、环保等领域。本文结合两者的优点,以铁掺杂大孔碳作为修饰材料增加电极灵敏度,以邻苯二胺和羟丙基-β-环糊精为双功能单体构筑分子印迹结构,利用电聚合的方法制备了盐酸洛美沙星分子印迹电化学传感器。该传感器选择性好,抗干扰能力强,灵敏度、准确度和精确度高,可应用于环境水样和牛奶中盐酸洛美沙星的检测。更多还原

【Abstract】 The Fe-doped macroporous carbon（Fe-MPC） was synthesized by a pyrolysis method in the N₂ atmosphere using polymethyl methacrylate（PMMA） as template, sucrose, FeCl₃ and polypyrrole as the carbon, iron and nitrogen precursors, respectively.The morphology and chemical composition of Fe-MPC was characterized by scanning electron microscopy（SEM）, X-ray diffraction（XRD） and nitrogen adsorption-desorption.The lomefloxacin sensor was constructed on Fe-MPC modified gold electrode via cyclic voltammetry electropolymerization of o-phenylenediamine and hydroxypropyl-beta cyclodextrins（HP-β-CD） in the presence of lomefloxacin.The electrochemical behavior of the sensor was studied with K₃[Fe（CN）₆] solution containing 0.1 M KCl as a probe by cyclic voltammetry（CV）, differential pulse voltammetry（DPV）, amperometric i-t response and electrochemical impedance spectroscopy（EIS）.The sensor exhibits good linear to lomefloxacin concentration in the range from 1.0×10^-9 to1.2×10^-7 mol·L^-1 with a detection limit of 2.0×10^-10 mol·L^-1（S/N=3）.It also displayed high selectivity, excellent stability and good reproducibility.The developed sensor was applied to detect lomefloxacin in water and milk samples.更多还原