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红树角果木内生真菌次级代谢产物的研究

Isolation and structure elucidation of secondary metabolites from mangrove endophytic fungus Trichoderma viride sp.JJM22

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【作者】 吴家婷郑彩娟陈光英

【Author】 Jia-Ting Wu;Cai-Juan Zheng;Guang-Ying Chen;Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education,Hainan Normal University;

【机构】 海南师范大学教育部热带药用植物化学重点实验室化学与化工学院

【摘要】 <正>研究红树林植物角果木茎部内生真菌Trichoderma viridesp.JJM22次级代谢产物。用硅胶柱层析、制备薄层层析和重结晶等方法,从该菌发酵液的乙酸乙酯萃取相中分离获得6个次级代谢产物(图1)。运用现代波谱技术以及文献数据对照,鉴定其结构分别为

【Abstract】 The secondary metabolites of the medicinal mangrove endophytic fungus Trichoderma viride sp.JJM22 were firstly studied.Six compounds were isolated from the ethyl acetate extract of the fermentation using silica gel column chromatography,preparative thin layer chromatography and recrystallization.The structures of these compounds were identified as 1-(2,6-dihydroxyphenyl)butan-1-one(1),2,4-dihydroxy-5-methylacetophenone(2),diapporthin(3),helicascolide A(4),β-sitosterol(5) and β-sitostenone(6)(figure 1) by comprehensive spectroscopic characterizations and comparison with reported data.Compounds 1 to 6 were isolated from mangrove endophytic fungus for the first time.

【基金】 国家自然科学基金(NSFC 21162009);中国科技部973项目(2014CB560714)
  • 【会议录名称】 中国化学会第十九届全国有机分析及生物分析学术研讨会论文汇编
  • 【会议名称】中国化学会第十九届全国有机分析及生物分析学术研讨会
  • 【会议时间】2017-03-30
  • 【会议地点】中国四川成都
  • 【分类号】TQ920.1
  • 【主办单位】中国化学会
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