【作者】 许龙斌； 马品一； 宋大千； 王兴华；

【Author】 Longbin Xu;Pinyi Ma;Daqian Song;Xinghua Wang;College of Chemistry,Jilin University;

【机构】 吉林大学化学学院；

【摘要】 设计合成了一个新的基于罗丹明B的,用于检测Fe³⁺的荧光、比色探针（Py-rh）。此探针表现出了较好的溶解性、较高的Fe³⁺选择性和生物兼容性,不受其他正离子的干扰。在水/甲醇体系下,Fe³⁺可以使探针的螺环打开而发出荧光,产生70倍的荧光增强。此外,探针成功应用在了生物体系中并且得到了满意的效果。更多还原

【Abstract】 A novel rhodamine-based colorimetric and fluorescent chemosensor（Py-rh） has been synthesized as binding site for Fe³⁺.Py-rh exhibited highly selective and sensitive recognition toward Fe³⁺.Upon interaction with Fe³⁺ in H2 O/acetonitrile（1:9 v/v）,the spirolactam of Py-rh was opened.It caused the significant enhancement of fluorescence intensity.Upon excitation at 540 nm,Py-rh displays a 70-fold fluorescence enhancement.In addition,fluorescence imaging experiments of Fe³⁺ in living cells demonstrate that Py-rh can be successfully application in biological system with satisfying results.更多还原