【作者】 曹杨羊； 毛达杰； 王维伟； 杜晓华；

【Author】 Cao Yang-yang;Mao Da-jie;Wang Wei-wei;Du Xiao-hua;Catalytic Hydrogenation Research Center, Zhejiang University of Technology, Zhejiang Key Laboratory of Green Pesticides and Cleaner Production Technology, Zhejiang Green Pesticide Collaborative Innovation Center;

【机构】 浙江工业大学催化加氢研究中心浙江省绿色农药清洁生产技术研究重点实验室浙江省绿色农药协同创新中心；

【摘要】 以取代吡啶为原料,与4-羟基苯硼酸经Suzuki偶联反应制得苯基吡啶类化合物,再与(E)-2-氯甲基-α-甲氧亚胺基苯乙酸甲酯或(E)2-氯甲基-α-甲氧丙烯基苯乙酸甲酯发生亲核取代反应合成了43个含吡啶基苯结构的醚菌酯衍生物,其结构均通过NMR和HRMS确证。初步除草活性测定结果表明,部分化合物具有良好的除草活性,其中A01和A04在15g.a.i/ha剂量下,对苘麻、小藜等杂草的抑制率达100%,同时A01和A04对小麦具有一定安全性,在小麦和小藜之间的选择性非常好。更多还原

【Abstract】 Forty-three novel Kresoxim-methyl were synthesized from 4-hydroxyphenyl boric acid and substituted pyridines via Suzuki cross-coupling reaction and nucleophilic substitution.The structures of all compounds were confirmed by NMR and HRMS.Preliminary herbicidal activity assays indicated that part of the compounds have good herbicidal activity.At 15 g a.i./ha,compounds A01 and A04 showed 100% inhibition against abutilon and Chenopodium serotinum.At the same time,A01 and A04 have certain safety to wheat,and the selectivity between wheat and Chenopodium serotinum is very good.更多还原