Muscone/RI7217 co-modified DTX liposomes enhance the chemotherapeutic effect of glioma in brain

【作者】 齐娜； KANG Shuangming； DUAN Wenjuan； ZHANG Shangqian；

【Author】 QI Na;KANG Shuangming;DUAN Wenjuan;ZHANG Shangqian;Guilin Medical University;Shenyang Pharmaceutical University;

【机构】 桂林医学院； Shenyang Pharmaceutical University； Guilin Medical University；

【摘要】 <正>Glioma is one of the most aggressive malignant diseases for human health.It is difficult to completely resect due to their invasiveness[1].In view of the selective permeability of the blood-brain barrier(BBB),most chemotherapeutic drugs are difficult to enter the brain[2].The targeted delivery,as a non-invasive approach,is a major strategy for the development of treatments in brain tumor.The transferrin receptor is更多还原