【作者】 张理伟； 李金； 丛馨； 胡晓晟； 李丹； 吴立玲； 华红； 俞光岩； Alexander Ross Kerr；

【Author】 Li-Wei Zhang;Jin Li;Xin Cong;Xiao-Sheng Hu;Dan Li;Li-Ling Wu;Hong Hua;Guang-Yan Yuc;Alexander Ross Kerrd;Department of Oral Medicine, Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology;

【机构】 北京大学口腔医学院口腔黏膜科口腔颌面外科；

【摘要】 背景:口腔癌是全球最常见的癌症之一。然而,中国口腔及口咽癌的流行病学趋势尚不清楚。本研究旨在评估2005年至2013年中国口腔及口咽癌的发病率和死亡率趋势。方法:采用中国国家癌症登记中心和国际癌症研究机构提供的数据进行分析。确定了世界人口的年龄标准化率。结果:2005年至2013年,我国新增口腔及口咽癌病例353,196例。发病率呈波动趋势,在2007年达到显著高峰。在研究期间,共有149,761人死于口腔及口咽癌,死亡率自2009年后死亡率开始显著增加。其中,发生于口腔和舌头的癌症是所有口腔及口咽癌中最常被诊断出的肿瘤,并且是导致死亡的主要原因。男性比女性更易好发口腔及口咽癌,预估口腔及口咽癌的粗发病率估计在未来20年内会增加。结论:口腔及口咽癌的发病率在2005年至2013年间呈波动趋势,而死亡率则在2009年后呈上升趋势。本文预计未来20年中国口腔及口咽癌的负担将更加沉重。更多还原

【Abstract】 Background: Oral and oropharyngeal cancers are among the most commonly occurring cancers globally. However, the epidemiological trends of oral and oropharyngeal cancers in China are not well known. This study aimed to assess the incidence and mortality trends of oral and oropharyngeal cancers in China from 2005 to 2013. Methods: Data provided by the National Central Cancer Registration of China and the International Agency for Research on Cancer was used in the analysis. Agestandardized rates by world population were determined. Results: There were 353,196 new registered oral and oropharyngeal cancer cases from 2005 to 2013 in China. The incidence rate fluctuated, with a notable peak in 2007. A total of 149,761 deaths from oral and oropharyngeal cancers occurred during the study period. The mortality rate began to increase significantly after 2009. Cancers localized to the mouth and tongue were the most frequently diagnosed and the leading causes of death among all oral and oropharyngeal cancers. Males were more susceptible than females to oral and oropharyngeal cancers. The crude incidence rates of oral and oropharyngeal cancers were estimated to increase over the next 20 years. Conclusion: The incidence of oral and oropharyngeal cancers fluctuated from 2005 to 2013, whereas the mortality rate demonstrated an upward trend after 2009. A heavier burden from oral and oropharyngeal cancers was predicted in the next two decades in China.更多还原