【作者】 邓志威； 李璟； 许美凤； 刘鹏； 耿珠峰；

【Author】 DENG Zhi-wei;LI Jing;XU Mei-feng;LIU Peng;GENG Zhu-feng;Analytical & Testing Center, Beijing Normal University;National Center of Biomedical Analysis;

【机构】 北京师范大学分析测试中心； 国家生物医学分析中心；

【摘要】 对核磁共振的特点及其在药物分析鉴定中应用的技术优势进行了分析。并通过实例展示了核磁共振检测试验方法多、信息丰富和定量分析方法灵活等技术特点。在3个具体实例中,利用核磁共振技术同步实现了混合物样品中主要成分或异构体的认定和含量(或相对含量)测量,达到了"快速"检测的效果。更多还原

【Abstract】 The advantages and applications of NMR in the analysis and identification of pharmaceutical materials were discussed, based on paper investigation and our own experience. The real cases showed that NMR could play an unique role in the pharmaceutical assay due to its distinctive technical characteristics,such as multi-methods available, plenty of information provided and flexibility of qNMR. In these cases,the main components in each of mixtures were identified and their contents( or relative cintens) were determined simultaneously by NMR techniques within a relatively short time.更多还原