【作者】 王琼； 张立婷； 陈红；

【机构】 兰州大学第一医院东岗院区肝病中心；

【摘要】 目的探讨肝硬化门静脉高压症脾切除术后门静脉血栓(portal vein thrombosis,PVT)形成的相关危险因素。方法,选取兰州大学第一医院东岗院区普外科2013年10月至2017年3月行脾脏切除+食管静脉曲张离断术的65例肝硬化患者。结果肝硬化门静脉高压症病人术后PVT发生率为30%(20/65),单因素分析结果显示术后门静脉主干直径增宽、脾静脉增宽、门静脉血流速度减慢、D-二聚体升高、抗凝血酶-III降低,术前血小板数量、脾脏体积与PVT发生相关(P<0.05)。Logistic回归多因素分析结果显示D-二聚体与门静脉主干宽度、术前血小板数量是预测术后PVT形成的独立危检因素。结论肝硬化门脉高压症术后门静脉血栓发生率较大,临床上应积极采取预防措施降低血栓的发生率。更多还原

【Abstract】 Objective To study the related risk factors of portal vein thrombosis after surgery for cirrhotic portal hypertension.The clinical data 65 consecutive patients with splenetomy and devascularization between October 2013 and March 2017 in Donggang branch of the first hospital of Lanzhou University.Results 20 patients were occurred portal vein thrombosis,the overall icdence of PVT was 30%.Univariate analysis showed that wilder portal vein diameter,wilder splenic vein,slower portal vein blood flow,higher leves of D-dinner,reduction of antihrombin-III,Platelet count、splentic volume before surgery for cirrhotic portal hypertension were correlated with the incidence of PVT(P<0.05).Logistic regression analysis showed that higher leves of D-dinner、wilder portal vein diameter、Platelet count before surgery were independent risk fators of PVT after surgery for cirrhotic portal hypertension patients.Conclusion The incidence of portal vein thrombosis in patients with surgery for cirrhotic portal hypertension was high,we should take positive measures to reduce it.更多还原