【作者】 俞立飞； 黄文豹； 许湘飞； 金洁； 张永乐； 梁伟峰；

【Author】 YU Li-fei;HUANG Wen-bao;XU Xiang-fei;JIN Jie;ZHANG Yong-le;LIANG Fei-feng;Department of Infectious Diseases,Hangzhou First People’s Hospital;Department of Clinical Laboratory,Tongde Hospital Of Zhejiang Province;Department of Infectious Diseases,the First Affiliated Hospital,Zhejiang University School of Medicine;

【机构】 杭州市第一人民医院感染科； 浙江省立同德医院检验科； 浙江大学医学院附属第一医院感染科；

【摘要】 随着2015年中国自身免疫性肝炎(AIH)专家共识发布,AIH越来越被临床医生关注。但其确切的病因及发病机制仍不完全明确,目前认为与多种基因和免疫异常相关。本文就基因、调节免疫和效应免疫机制在AIH发病机制中的研究进展做简要综述。更多还原

【Abstract】 With Chinese expert consensus of autoimmune hepatitis(AIH) in 2015 issued,AIH is more and more concerned by clinical physicians.But the exact etiology and pathogenesis is still unclear.It is thought to be associated with various genetic and immunological abnormalities.The review summaries the research advance about genetics,regulatory and effector immune mechanisms in AIH pathogenesis.更多还原