【作者】 张颖； 朱良均； 杨明英；

【Author】 ZHANG Ying;ZHU Liang-jun;YANG Ming-ying;Institute of Applied Bioresources,Zhejiang University;

【机构】 浙江大学应用生物资源研究所；

【摘要】 丝素蛋白作为一种生物相容性优良、免疫原性低、无毒的可降解生物材料,得到生物医学领域的广泛关注,特别是由其合成的丝素蛋白微球因高载药率、依赖pH靶向缓释的优良特性,成为热门的药物载体材料。本文综述了丝素蛋白微球的多种合成方式及其载药的实际应用。更多还原

【Abstract】 Silk fibroin has been wildly studied in biomedical fields,due to its well biocompatible,low immunogenicity and biodegradability.Silk fibroin microsphere has become a popular drug carrier material by having the advantages of high drug loading rate and its pH dependent release.This paper reviewed the synthesis of silk fibroin microshperes and their practical applications of loading drugs.更多还原