【作者】 亓鲁滨； 郭永先； 巩彦君； 于丽；

【Author】 Lubin Qi;Yongxian Guo;Yanjun Gong;Li Yu;Key Laboratory of Colloid and Interface Chemistry,Shandong University,Ministry of Education;

【机构】 山东大学； 山东大学胶体与界面化学教育部重点实验室；

【摘要】 多金属氧簇是一类优异的无机构筑单元,在催化、光电和生物等领域具有广阔的应用前景。表面活性剂包覆的多金属氧簇复合物兼具表面活性离子液体和多金属氧化簇的特点。本文利用双子表面活性离子液体[C₁₆-2-C₁₆im]Br₂和含稀土铕的多金属氧簇（Eu-POM）自组装制备了超分子纳米球。研究发现,静电作用和疏水作用是形成Eu-POM/[C₁₆-2-C₁₆im]Br超分子材料的主要驱动力;构筑的超分子杂化材料还具有良好的荧光性质和生物相容性,可以作为荧光探针用于生物成像。随后,以铜离子修饰Eu-POM/[C₁₆-2-C₁₆im]Br超分子复合物,制备了一种超分子传感器,并应用于快速检测硫化氢气体。发现,硫化氢的加入使得该传感器表现出了荧光猝灭和紫外吸收增强的双重信号变化,且具有良好的灵敏性和选择性,对硫化氢的检测限达到1.4μM。通过研究该超分子探针检测硫化氢的荧光猝灭机制,推测硫化氢和铜离子生成的硫化铜与激发态稀土铕之间的能量转移可能是导致荧光猝灭的主要原因。该研究工作对于诊断阿尔兹海默症、唐氏综合症等相关疾病有一定的指导意义。更多还原

【Abstract】 Polyoxometalates（POMs） are a kind of outstanding inorganic building block and intensively utilized in life science,catalytic and electronic field.Surfactant-encapsulated polyoxometalate complexes（SECs） possess properties of surface active ionic liquid（SAIL） and POMs.Nanostructured spheres fabricated by Na₉EuW₁₀O₃₆·32H₂O（Eu-POM） and gemini-type SAIL 1,2-bis（3-hexadecylimidazolium-1-methyl） butane bromide（[C16-2-C16 im]Br2）.Electrostatic interaction and hydrophobic interaction were proved to be the main driving forces of the self-assembled [C₁₆-2-C₁₆im]Br₂/Eu-POM hybrids.The complexes showed excellent fluorescence properties and fine biocompatibility,which were applied as promising agents for cell imaging.Then,the hybrids were modified with copper（II） ion and the as-prepared supramolecular fluorescence probe was used to rapid detection of H₂S.The copper（II） ion-modified supramolecular sensor（CSS）showed dual signals in the fluorescent intensity and UV absorbance for H₂S detection with high sensitivity and selectivity.The detection limit of CSS is 1.4 μM.Furthermore,the mechanism of fluorescence quenching was also investigated.CuS generated by the reaction between Cu²⁺ and H₂S was testified to act as a quencher,and the energy transfer between it and the excited state of Eu³⁺ was speculated to be responsible for the fluorescence quenching.This work is meaningful for diagnose of some relevant diseases,such as Alzheimer’s disease and Down’s syndrome.更多还原