【作者】 肖桂荣； 徐珽； 吕晓菊；

【Author】 Xiao Guirong;Xu Ting;Lv Xiaoju;Department of Clinical Pharmacy,West China Hospital of Sichuan University;Center of Infectious Diseases.West China Hospital of Sichuan University;

【机构】 四川大学华西医院临床药学部(药剂科)； 四川大学华西医院感染性疾病中心；

【摘要】 目的:通过伏立康唑血药浓度监测对患者进行个体化药学服务,促进伏立康唑的合理应用。方法:结合临床药师工作实践,总结对伏立康唑血药浓度监测患者的药学服务内容与方法。结果:临床药师应关注患者服药方法、合并用药相互作用、药物代谢基因等对伏立康唑血药浓度监测结果的影响,对血药浓度监测结果不达标的患者进行原因分析并给药用药方案调整建议。结论:临床药师根据伏立康唑血药浓度监测结果开展个体化药学服务,有利于促进伏立康唑的安全合理使用。更多还原

【Abstract】 OBJECTIVE By monitoring serum concentrations of voriconazole in patients,to promote individualized pharmaceutical care and to improve the rational voriconazole.METHODS Based on clinical pharmacist s work practice,the contents and methods of pharmaceutical care were summarized for patients with voriconazole blood concentrations monitored.RESULTS Clinical pharmacists needed to pay more attention an factors that could affect results of voriconazole blood concentration,such as methods of taking medicine,drug interactions,drug metabolism genes.For those with blood concentration beyond the therapeutic range,abnormal results analysis and dosage regimen adjustment suggestion should be carried out.CONCLUSION According to the monitoring results of voriconazole blood drug concentration,the clinical pharmacist can carry out individualized pharmaceutical care,which is beneficial to promote safety and rational use of voriconazole.更多还原