【作者】 解飞； 周霖； 蔡斌； 甘露； 雷蕾； 蒋瑾瑾； 陈若华；

【Author】 XIE Fei;ZHOU Lin;CAI Bin;GAN Lu;LEI Lei;JIANG Jin-jin;CHEN Ruo-hua;Department of Pediatrics,Changhai Hospital Affiliated to the Second Military Medical University;

【机构】 第二军医大学附属长海医院儿科；

【摘要】 目的:分析29例自身免疫性溶血性贫血患儿的病因及治疗。方法:对长海医院2013年1月至2015年12月住院29例自身免疫性溶血性贫血患儿进行回顾分析。结果:29例中10例原发,19例继发,其中11例发生于感染后。主要临床表现为面色苍白、黄疸、尿色加深及肝脾肿大,21例Coombs试验阳性。结论:治疗AIHA的首选药物为肾上腺皮质激素,丙种球蛋白对于单用肾上腺皮质激素效果不满意者,可提高疗效、缩短疾病病程。对重度AIHA患儿可予输血治疗,但需要输血时应严格配血。同时,原发病的治疗,也对疗效的提高起着关键作用。更多还原

【Abstract】 Objective:To analyze the etiology and treatment of autoimmune hemolytic anemia in children.Methods:Twenty nine patients with autoimmune hemolytic anemia hospitalized in Changhai hospital from January of 2013 to December of 2015 were retrospectively analyzed.Results In 29 cases,10 cases were primary,and the other 19 cases were secondary.11 cases of the 19 cases were secondary to the infection.Clinical manifestations are mainly performance for jaundice,pale,urine color deepened and hepatosplenomegaly,Coomb’ s test was positive in 21 cases.Conclusion:Usually glucocorticoid was used as first-line therapy in AIHA.When therapy efficacy is not ideal with hormone,The course of disease can be shorten with gamma globulin.For paitients with severe AIHA,blood transfusion should be used to reduce the acute complications.Meanwhile,the treatment of primary disease is also important to improve curative effect.更多还原