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几种美白剂抑制酪氨酸酶活性的研究
Study oninhibition of Tyrosinase activity of several whitening materials
【作者】 刘琦; 刘洋; 吴金昊; 陶丽莉; 王楠; 赵华;
【Author】 LIU Qi;LIU Yang;WU Jin-hao;TAO Li-li;WANG Nan;ZHAO Hua;Beijing Daily Chemical Association;China Association of Fragrance Flavor and Cosmetic Industries;Beijing Key Laboratory of Plant Resources Research and Development;China Cosmetics Research Center of Beijing Technology and Business University;
【机构】 北京日化协会; 中国香料香精化妆品工业协会; 北京市植物资源研究开发重点实验室; 北京工商大学中国化妆品研究中心;
【摘要】 对几种美白剂抑制酪氨酸酶活性的作用进行测定。以L-酪氨酸为底物,测定一定质量分数下的美白剂对酪氨酸酶活性具有良好的抑制效果;选用α-熊果苷测定实验方法的重现性与精密度,相对标准偏差分别为1.3%与0.96%;几种美白剂对酪氨酸酶活性具有抑制效果,抑制作用为可逆抑制,抑制类型为非竞争性抑制。
【Abstract】 Measure the effect of inhibiting tyrosinase activity on several whitening materials,With L-tyrosine as substrate for determination of certain concentration of whitening agent has good inhibition effect on the activity of tyrosinase.Use α-arbutin to measure the method of the experiment’s reproducibility and precision,RSD were 1.3%and 0.96%.Identified these whitening materials to inhibit tyrosinase activity were reversible inhibition,the type were noncompetitive inhibition.
【Key words】 inhibit tyrosinase activity; reproducibility; precision; dose-effect-relation-ship; reversable inhibition;
- 【会议录名称】 第十一届中国化妆品学术研讨会论文集
- 【会议名称】第十一届中国化妆品学术研讨会
- 【会议时间】2016-06-15
- 【会议地点】中国上海
- 【分类号】TQ658
- 【主办单位】中国香料香精化妆品工业协会