MicroRNA 29 familyand Parkinson’s disease

【作者】 Xiaochen Bai； Yilin Tang； Mei Yu； Lei Wu； Fengtao Liu； Zishan Wang； Jinghui Wang； Jian Wang； 黄芳；

【Author】 Xiaochen Bai;Yilin Tang;Mei Yu;Lei Wu;Fengtao Liu;Zishan Wang;Jinghui Wang;Jian Wang;Fang Huang;The State Key Laboratory of Medical Neurobiology and the Institutes of Brain Science, Shanghai Medical College, Fudan University;Department of Neurology, Huashan Hospital, Fudan University;

【机构】 The State Key Laboratory of Medical Neurobiology and the Institutes of Brain Science, Shanghai Medical College, Fudan University； Department of Neurology, Huashan Hospital, Fudan University；

【摘要】 <正>Parkinson’s disease is the second most common neurodegenerative disease,characterized by the progressive loss of dopaminergic neurons in the substantia nigra of the midbrain.There is still a lack of effective diagnosis and treatments for PD.Micro RNAs have been proved to play an important role in PD pathology.Micro RNA29 family(mi R-29s)is including two gene clusters:mi R-29a/b1 and mi R-29b2/c,which更多还原