【作者】 刘东旭； 李亮； 刘洪；

【Author】 Dongxu Liu;Liang Li;Hong Liu;Department of Orthodontics,College of Stomatology,Shandong University,Shandong Provincial Key Laboratory of Oral Tissue Regeneration;Department of Orthodontics,Yantai Stomatological Hospital;

【机构】 山东大学口腔医学院口腔正畸教研所；

【摘要】 影响上呼吸道通气功能的主要因素是呼吸气流变化。此研究旨在通过计算流体动力学模拟观察AngleⅡ~1伴下颌后缩处于生长期患者经双HE垫治疗后咽部气流变化特征。锥形束CT扫描已完成双HE垫矫治的30例患者及尚未接受双HE垫矫治的30例患者,以重建咽部形态。经计算流体动力学模拟,进一步分析咽部气压下降与咽部形态学参数之间相互关系。在吸气过程中,我们发现最小气压出现在咽喉,而气压下降最大值及速率最大值出现在口咽部。经双HE垫矫治后,气流特点在口咽、喉咽部有显著改变,最大改变出现在口咽部。我们观察发现口咽部气压下降值与口咽体积(r=0.694,p=0.001),与口咽横截面积(r=0.859,p=0.000),与口咽横截面积最小值与平均值比率(r=0.898,p=0.000)呈显著相关。研究表明,在下颌前伸后口咽体积、横截面积增加,面积分布更加均匀,咽部气流呈积极性改变。更多还原

【Abstract】 The flow dynamics of respiratory airflow is the basic factor that influences the ventilation function of the upperairway.This research aimed to investigate the pharyngeal flow field characteristics after Twin Block(TB)treatment in growing patients with Class Ⅱ1 and mandibular retrognathia by computation fluid dynamics(CFD)simulation.Cone beam computed tomography(CBCT) scans of patients who have completed TB treatment(n=30)and about to accept TB treatment(n=30) were reconstructed.After CFD simulation,correlations between thepharyngeal pressure drop and morphological parameters were further analyzed.During inspiration,we found thatthe pressure minimum occurred in the hypopharynx,while the maximum pressure drop and velocity was located inthe oropharynx.After TB treatment,the oropharynx and hypopharynx showed significant differences in airflowfeatures,and the most obvious change was observed in the oropharynx.A significant correlation was discoveredbetween the change amount of oropharyngeal pressure drop and volume(r=0.694,p=0.001),mean cross-sectionalarea(r=0.859,p=0.000),and ratio of the minimum and mean cross-sectional area(r=0.898,p=0.000) of theoropharynx.Our research suggested that the pharyngeal airflow characteristics response positively to mandibularadvancement with the enlargement in volume,cross-sectional area and more uniform oropharyngeal areadistribution.更多还原