【作者】 郭玉明； 马晓明； 白正宇； 王晓兵； 王魁； 杨林；

【Author】 Yuming Guo;Xiaoming Ma;Zhengyu Bai;Xiaobing Wang;Kui Wang;Lin Yang;School of Chemistry and Chemical Engineering,Henan Normal University;

【机构】 河南师范大学化学化工学院；

【摘要】 受生物矿化启发,我们以细胞、蛋白质等为基质,模拟生物矿化条件,合成了多种无机纳米组装结构并研究了其形成机理和性能。一是在细胞内合成了碳酸钙、羟基磷灰石、金属等纳米组装结构;二是以生物分子为基质作用下由纳米粒子单元构筑成多层壳、核壳、多级孔、花形等不同纳米组装体;三是模拟生物矿化合成了系列金属硫(硒)化合物/蛋白质杂化的纳米线、纳米棒和量子点材料;四是模拟生物矿化合成了金属纳米组装结构。通过理论计算研究了它们的形成机理,并认识了它们在抗癌药物可控靶向释放、荧光探针、重金属吸附、抑制癌细胞增殖、荧光标记等方面的潜在性能及其与组成、结构、晶型的相关性。更多还原

【Abstract】 Inspired by biomineralization,different kinds of inorganic nanoassembled structures were prepared using cells and proteins as matrices.The formation mechanisms and properties were studied in detail.Firstly,CaCO₃,HAP,and metallic nanoassembled structures were prepared in cells.Secondly,nanoassembled structures including multishell hollow spheres,core/shell,multimodal porous,and flower-like structures assembled by nanoscaled build units were prepared using biomolecules as matrices.Thirdly,metal selenide（telluride）/proteins hybrids of nanowires,nanorods and quantum dots were prepared.Fourthly,metallic nanoassembled structures were prepared.The formation mechanisms were studied through theoretical calculation.Finally,the corresponding applications in different fields were evaluated.更多还原