【作者】 王萍； 江树人； 张宏军； 王鹏； 任红； 王秋霞； 周志强；

【Author】 WANG Ping;JIANG Shu-ren;WANG Peng;REN Hong;WANG Qiu-xia;ZHOU Zhi-qiang;College of Science,China Agricultural University;

【机构】 中国农业大学理学院；

【摘要】 采用高效液相色谱法、涂敷型手性固定相纤维素-三(3,5-二甲基苯基氨基甲酸酯)(CDMPC)对外消旋除草剂乙氧呋草黄进行拆分,并制备了两种光学纯对映体,采用生物测定方法对二者的生物活性进行了初步研究。结果表明,用本方法制备的光学纯对映体纯度达到97%以上;供试植物材料品种间对该化合物的敏感性差异显著;右旋体对黄瓜生长抑制率为左旋体的1.78~2.25倍;除黄瓜外,两个对映体对小麦、高梁、油菜等供试植物均表现出一致的生物活性。更多还原

【Abstract】 Enantiomeric resolution and preparation of Ethofumesate was achieved by using of HPLC Cellulose-tris(3,5-dimethylphenylcarbamate)(CDMPC) chiral stationary phase.The enantiomeric bioactivky was also primarily stated by bioassay with different plant materials.Optical purity of the two enatiomers were more than 97% prepared by this method.The dextroisomer showed 1.78-2.25 more potent on cucumber fresh weight inhibition than that of laevoisomer,while showed quite equal performace on inhibition of other plant materials.The sensitivities of tested material to this chemical were significantly differed among species.更多还原