【作者】 石大玲； 汪学红； 徐传智；

【Author】 SHI Da-ling;WANG Xue-hong;XU Chuang-zhi;Department of Physical Education,Huazhong University of Science and Technology;Wuhan Institute of Physical Education;

【机构】 华中科技大学同济医学院； 武汉体育学院；

【摘要】 目的:研究运动训练对大鼠吸烟引起的肺组织病理变化。方法:复制大鼠吸烟模型后,进行运动训练,测定大鼠气道反应性、血浆皮质醇浓度,行苏木精——伊红染色观察肺组织病理变化。结果:①吸烟组的气道反应性明显高于正常对照组(P<0.05),而吸烟运动组的气道反应性显著低于吸烟组(P<0.01),且与正常对照组无明显差异;②吸烟运动组运动后血浆皮质醇浓度明显高于运动前(P<0.01),但全部运动结束后次日晨测定的血浆皮质醇浓度与运动前无明显差异(P>0.05);③苏木精——伊红染色显示,吸烟组肺组织出现明显的慢性炎症反应,吸烟运动组比吸烟组炎症反应轻。结论:适当的运动能降低由吸烟引起的气道高反应性。更多还原

【Abstract】 Objective To study the effects of exercise training on the rat smoking- induced pulmonary pathological changes.Methods Rat smoking model was made and subjected to exercise training.Airway obstructive response,serum Cortisol contents and pulmonary pathological changes in rats after smoking were investigated.Results In smoking group,airway obstructive response was significantly greater than in normal control group(P <0.05),while that in smoking exercise group significantly less than in smoking group(P <0.01),and had no significant difference from that in normal control group.In smoking exercise group,serum Cortisol content after exercise was significantly higher than that before exercise(P <0.01),but that determined on the next day morning after finishing exercise training had no significant difference from that before exercise(P >0.05).Chronic inflammatory reaction was obvious in pulmonary tissue of smoking group,and that in smoking exercise group was milder than smoking group.Conclusion Exercise training could alleviate the smoking- induced airway obstructive response and pulmonary pathological changes.更多还原