Highly Enantioselective Reaction of 2-Oxindole with(3-Indonyl)methanol Catalyzed by Cooperation of Lewis Acids and Organocatalyst for the Synthesis of Chiral Indole-linker-Oxindole Compounds

【作者】 任传利； 张涛； 王东； 陈拥军； 刘利；

【机构】 中国科学院化学研究所； 中国科学院大学；

【摘要】 <正>The combination of transition metal catalysts and organocatalysts has emerged as a powerful tool for the development of innovative transformations.^[1]The cooperative catalytic system has been widely applied in theα-alkylation of carbonyl compound to enhance the reactivity,improve the efficiency and enforce the stereocontrol of existing reaction.^[2]However,it is noteworthy that most of the organocatalyst used in the更多还原