【作者】 张文晶； 张艺轩； 史鑫浩； 梁聪； 鲜跃仲； 金利通；

【Author】 Wenjing Zhang;Yixuan Zhang;Xinhao Shi;Cong Liang;Yuezhong Xian;Litong Jin;Department of Chemistry, East China Normal University;

【机构】 华东师范大学化学系；

【摘要】 <正>复合纳米微粒的合成、表征以及应用是近来化学、材料以及生物学等领域关注的焦点。其中,具有光学特性与磁性的复合纳米微粒的研究更受到广大科学工作者的青睐。成功实现复合纳米微粒在生物医学领域的应用,其核心是构建稳定性高、可靠性好、生物相容性强、简单易行的合成方法。许多光磁复合材料研究更多还原

【Abstract】 The paper reports on covalent clicking of rhodamine-B(Rh B) bearing a terminal azide group to alkyne-terminated superparamagnetic iron oxide nanoparticles(SPIONs) Fe3O4@Si O2 via the copper(I)-catalyzed Huisgen azide-alkyne 1,3-dipolar cycloaddition(Cu AAC) reaction. The course of the reaction was followed using powder X-ray diffractometry(XRD), transmission electron microscopy(TEM), Fourier transform infrared(FTIR) spectroscopy, fluorescence, and vibrating sample magnetometer(VSM). The Rh B labeled SPIONs exhibit stable fluorescent spectrum and no detectable leakage of the fluorescent dye because the resulting 1, 4-disubstituted 1, 2, 3-triazole ring formed during the process of click reaction is thermally stable and relatively inert to hydrolysis, oxidation, and reduction. Furthermore, the excellent biocompability of the rhodamine-B decorated Fe3O4 nanopaticles shows potential applications for electrochemical biosensors fabrication.更多还原