探讨脓毒血症预后评估中降钙素原和N末端前体脑钠肽的临床意义

【作者】 叶钢；

【机构】 首都医科大学附属北京潞河医院；

【摘要】 目的:探讨脓毒血症预后评估中降钙素原和N末端前体脑钠肽的临床意义。方法:分析我院56例脓毒血症患者的临床资料,将其预后结果分为死亡组和存活组,对比患者发病期间降钙素原(PCT)和N末端前体脑钠肽(NT-proBNP)及急性生理和慢性身体健康状况,并分析两种标记物对评估脓毒血症患者预后的临床意义。结果:两组患者在PCT、NT-proBNP以及身体生理状况方面具有差异统计学意义(P<0.05),并且两种标记物与患者的身体生理状况存在密切的关系。结论:对于脓毒血症患者预后的良好判断,可以联合PCT和NT-proBNP进行检测,其特异性更是高达90.0%,对患者的良好预后有较为明显的预测价值。更多还原

【Abstract】 objective:to study the prognosis of sepsis assessment of calcitonin original and N terminal precursor of brain natriuretic peptide clinical significance.Methods:analyzed the clinical data of 56 patients with sepsis and its outcome can be divided into death and survival groups,compared to patients during the onset of calcitonin original precursor(PCT) and N terminal brain natriuretic peptide(NT-proBNP) and acute physiology and chronic health conditions,and analyze the two kinds of markers to evaluate the prognosis of patients with sepsis clinical significance.Results:two groups of patients in the PCT,NTproBNP and body physiology has a statistically significant difference(P<0.05),and two kinds of markers there is a close relationship with the patient body physiological condition.Conclusion:for judging the prognosis of patients with sepsis is good,can joint the PCT and the NT-proBNP testing,its specificity is as high as 90.0%,with good prognosis in patients with more obvious predictive value.更多还原