【作者】 闵璇宇； 张晓红； 娄志超； 张亚男； 胡晓丹； 张海黔；

【Author】 MIN Xuan-yu;ZHANG Xiao-hong;LOU Zhi-chao;ZHANG Ya-nan;HU Xiao-dan;ZHANG Hai-qian;Department of Nuclear Science and Engineering,Nanjing University of Aeronautics and Astronautics;

【机构】 南京航空航天大学材料科学与技术学院；

【摘要】 在突发性放射性事故中,需要使用生物剂量计对事故区域人员进行快速鉴别以确定该类人员是否受到电离辐射照射。本实验通过测量受到不同剂量γ辐射的小鼠在照后不同时间点的血清铁(Ⅲ)浓度,建立生物体内血清铁浓度与辐射剂量的剂量效应关系,对基于小鼠血清铁的生物剂量计进行初步研究。实验结果显示血清铁浓度与辐照剂量成正比,剂量效应关系明显,利用所得剂量效应关系估测的受照小鼠剂量与"双盲"剂量相近。因此采用基于血清铁的新型生物剂量计来估测人员的受照剂量是简便、迅速并且有效的。更多还原

【Abstract】 A new biological dosimeter based on serum iron was developed.We use biological dosimeter for rapid identification of large numbers of personnel were irradiated,and eliminate some people were irradiated by small doses who need no medical intervention in the sudden radioactive accident.The writer measured the concentration of serum iron(Ⅲ) of mice which were irradiated in the different dose and different time point between 0-16 d.The results show that serum iron concentration is in direct proportion to irradiation dose,and the dose-effect relationship of the indicator is obvious.Using the serum iron as a new type of irradiation of biological marker to estimate the dose of irradiated personnel is rapid,economic and effective.更多还原