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白藜芦醇抗紫外线所致豚鼠皮肤损伤作用

Resveratrol anti-ultraviolet-induced guinea pig skin injury

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【作者】 李文兴赵英

【Author】 LI Wen-Xing;ZHAO Ying;College of Pubic Health Sciences,Jilin University;Workers Hospital of Shanxi Coal Authority;

【机构】 吉林大学卫生检测中心实验室山西省煤炭厅职工医院

【摘要】 目的评价白藜芦醇在紫外线辐射(ultraviolet radiation,UVR)所致皮肤损伤中的作用。方法:正常皮肤在白藜芦醇和其药物载体基质的干预下经设计剂量紫外线照射后,将各组样本比较。结果:白藜芦醇组与自身空白对照组比较,豚鼠皮肤外观及各层组织未见明显差异;经过同样剂量紫外线照射,基质对照组皮肤外观及各层皮组织结构均可见显著改变。结论:研究初步表明白藜芦醇具有抗紫外线所致皮肤损伤特性。

【Abstract】 Objective:To Estimate on the protection effect of Stilbene on skin damage induced by ultraviolet radiation.Methods:After the normal skin in guinea pig under the intervene of Resveratrol was irradiated with over-dose of ultraviolet rays(UVB and UVA),the samples in every group were matched and compared.Results:The skin tissue in the Resveratrol intervene group irradiated by ultraviolet rays didn’t change obviously as compared with that in the self-control group.But,the damage skin tissue in the control group irradiated by ultraviolet did change significantly as compared with that in the Stilbene intervene group.Conclusion:Resveratrol is a good material to protect the skin from damage effect by ultraviolet radiation.

【关键词】 紫外线白藜芦醇皮肤损伤
【Key words】 ultraviolet radiationresveratrolskindamnification
  • 【会议录名称】 中国核科学技术进展报告(第三卷)——中国核学会2013年学术年会论文集第5册(辐射防护分卷、核化工分卷)
  • 【会议名称】中国核学会2013年学术年会
  • 【会议时间】2013-09-11
  • 【会议地点】中国黑龙江哈尔滨
  • 【分类号】R285.5
  • 【主办单位】中国核学会
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