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实时三维超声心动图定量评价冠心病患者PCI术前后左心室重构及逆转

Quantitative Assessment of Left Ventricular Remodeling and Reverse Remodeling in Patients with PCI by Real-time Three-dimensional Echocardiography

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【作者】 齐清华; 张连仲; 高传玉;

【Author】 Qi Qinghua;Zhang Lianzhong;Gao Chuanyu;Department of Ultrasound,First Affiliated Hospital of Zhengzhou University;Department of Ultrasound,Henan Provincial People’s Hospital;

【机构】 郑州大学第一附属医院超声科; 河南省人民医院超声科; 河南省人民医院心内科;

【摘要】 目的探讨实时三维超声心动图(RT3DE)评价冠心病患者冠状动脉介入治疗(PCI)术前后左心室构型变化的价值。方法将57例研究对象分为3组:正常对照组(A组)、急性心肌梗死组(B组)、陈旧性心肌梗死组(C组)。应用RT3DE对CAD患者术前,术后1个月及对照组进行检查,脱机软件分析得出左心室射血分数(LVEF)、舒张末容积(LVEDV)、峰值射血率(PER)、峰值充盈率(PFR),达到最小收缩容积时间的标准差及最大差值(Tmsv16-SD、Tmsv16-Dif)等参数,并将测值分别比较。结果 B组手术前各参数与A组比较差异具有统计学意义(P<0.05),术后各参数与A组比较无明显统计学意义(P>0.05),C组手术前后各参数与A组比较都具有统计学意义,术前比较(P<0.01),术后比较(P<0.05);B、C组各参数手术前后比较差异有统计学意义(P<0.05)。结论冠心病患者左心室发生了不同程度的重构,PCI治疗可使此类重构逆转,RT3DE为CAD患者PCI治疗术前后左心室构型变化的准确评价方法。

【Abstract】 Objective To assess the value of real-time three-dimensional echocardiography(RT3DE) in evaluation of the left ventricular configuration in patients with coronary artery disease(CAD) pre-and post-percutaneous coronary intervention(PCI).Methods Fifty-seven patients were divided into normal control(Group A).acute myocardial infarction(Group B),and old myocardial infarction(Group C).A series of left ventricular indices by RT3 DE examination were analyzed offline pre-and 1 month post-PCI operation,including left ventricular ejection fraction(EF),enddiastolic volume(EDV),the peak ejection rate(PER),peak filling rate(PFR),the maximal difference of time and standard deviation to the point of minimal systolic volume(Tmsv) of 16 segments(Tmsvl6-SD,Tmsvl6-Dif).Results There were significant differences of all pre-PCI parameters between group A and Group B(P<0.05),but no significant differences post-PCI(P>0.05).There were significant difference between pre-(P<0.01) and post-(P<0.05)PCI in Group C;There were significant differences between pre-and post-PCI in Group B and C(P<0.05).Conclusions Left ventricular remodeling could be found in patients with CAD.PCI might reverse left ventricular remodeling somewhat.RT3 DE could be a new valuable method of evaluating left ventricular configuration in patients with CAD pre-and post-PCI.

  • 【会议录名称】 《中国超声医学杂志》2011-2012年度评选优秀论文会议资料汇编
  • 【会议名称】《中国超声医学杂志》2011-2012年度评选优秀论文会议
  • 【会议时间】2013-08-23
  • 【会议地点】中国北京
  • 【分类号】R540.45;R541.4
  • 【主办单位】中国超声医学工程学会
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