【作者】 牟宽厚； 冯捷； 张宪旗； 周爱民；

【Author】 MOU Kuanhou,FENG Jie,ZHANG Xianqi,ZHOU Aimin( 1.Department of Dermatology,First Hospital of Xi’an Jiaotong University,Xi’an 710061;2.Department of Dermatology,First Hospital of Xi’an Jiaotong University,Xi’an 710004)

【机构】 西安交通大学第一医院皮肤科； 西安交通大学第二医院皮肤科；

【摘要】 目的研究浮萍、紫丹参乙醇提取物对体外培养的人黑素细胞生长的影响。方法通过测定黑素细胞酪氨酸酶活性、黑素含量及细胞增殖情况,了解药物浓度和黑素细胞生长的关系。结果浮萍、紫丹参醇提取物浓度在0～250μg/mL时对黑素细胞促生长作用明显,且呈剂量依赖关系。结论中药浮萍、紫丹参对体外黑素细胞促增殖作用显著。更多还原

【Abstract】 Objective To study the effect of alcohol- extracts of Herba Spirodelae (HS)and Radix Salviae Miltiorrhizae (RSM) on the growth of cultured melanocytes (MC).Methods MC were cultured with the alcohol- extracts of HS and RSM.Tyrosinase activity,melanin content and proliferation of the cells were checked.Cell growth curve was drawn out to evaluate the relationship of drug concentration and MC growth.Results HS and RSM at the concentrations of 0～ 200μ g/mL markedly promote the proliferation of MC in a dose- dependent manner.Conclusion HS and RSM can promote the proliferation of MC.更多还原