【作者】 吕蓓蓓； 邢杰； 谢春锋； 曲建博； 娄红祥；

【Author】 L Bei-bei XING Jie XIE Chun-feng QU Jian-bo LOU Hong-xiang (School of Pharmaceutical Sciences,Shandong University,Jinan 250012,China)

【机构】 山东大学药学院；

【摘要】 <正>苔藓植物在分类学上介于藻类植物和维管束植物之间,从形态学上可分为三类:角苔纲 (Hornworts)、苔纲(Liverworts)和藓纲(Mosses)。苔藓植物是活性天然产物的宝库,含有萜烯类、苯酚类、联苄类、黄酮类等化合物,其中联苄类化合物主要存在于苔类植物中,如片叶苔属更多还原

【Abstract】 Liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-ESI/MS/MS) in negative ion mode was used for the screening of b/s-bibenzyls in 2 bryophyte crude extracts (Marchantia polymorpha L.and Asterella angusta).To obtain the mass spectrometric characteristics of bisbibenzyls, 15 confirmed bis-bibenzyls compounds were investigated and the fragmentation patterns were proposed.Further characterization of each crude extract was performed using full scan and MS/MS production analysis.The confirmed or unconfirmed bis-bibenzyls were identified or proposed by comparison of the retention behavior,mass spectrometric and the UV spectroscopic data with confirmed bis-bibenzyls compounds.As a result,5/18,8/16 confirmed/unconfirmed b/s-bibenzyls were determined in the two crude extracts respectively.The method is simple, reliable and sensitive,and it could be used for screening other bis-bibenzyls analogs.更多还原