【作者】 陈建国； 王茵； 梅松； 来伟旗； 付颖； 胡欣；

【Author】 Chen Jian-guo, Wang Yin,Mei Song,et al (Institute of Health Food,Zhejiang Academy of Medical Sciences,Hangzhou,310013)

【机构】 浙江省医学科学院保健食品研究所；

【摘要】 目的探讨茶多糖是否具有降低血糖、改善糖尿病症状的作用。方法将四氧嘧啶导致的I型糖尿病小鼠随机分成4组,每天分别灌胃给予蒸馏水、茶多糖1．0、2．0、4．0g／kg bw。每天记录饮水量,每周称量体重1次, 连续4w,在实验中期(2w)、末期各测空腹血糖1次。结果茶多糖能明显缓解糖尿病小鼠“三多一少”症状,降低其空腹血糖,并存在剂量-反应关系。同时,茶多糖对本实验小鼠血糖值、饮水量之间相互影响存在明显正相关性;饮水量与体重之间存在负相关性。结论茶多糖具有降低糖尿病小鼠血糖,改善糖尿病症状的作用。更多还原

【Abstract】 Objective To investigate the.effects of tea polysaccharide(TP)on blood glucose and diabetic symptoms in mice.Methods Alloxan-induced diabetic mice were divided into 4 groups, and administered orally with saline,TP at doses of 1.0,2.0,4.0 gAg body weight,respectively for 4 weeks.Water intake and body weight were recorded daily and weekly respectively.Fasting blood samples were collected for measurement of glucose at the end of 2nd and 4th week.Results Symptoms of diabetic mice fed TP wete improved obviously .Their blood glucose concentration and water intake decreased significantly.On the other hand, their body weight increased obviously .There was positive correlation between blood glucose and water intake,but negative correlation between water intake and body weight.Conclusion TP can decrease blood glucose concentration and improve diabetic symptoms in mice.更多还原