【作者】 张丁； 张书芳； 李永利； 朱新朋； 郝大情； 张聪恪； 张榕杰；

【Author】 Zhang Ding, Zhang Shu-fang, Li Yong-li, Zhu Xin-peng, Hao Da-qing, Zhang Cong-ke, Zhang Rong-jie Henan Center for Disease Control and Prevention, Zhengzhou 450003, China

【机构】 河南省疾病预防控制中心；

【摘要】 目的:通过对中老年人补充复合营养素,探讨其对营养和免疫状况的影响。方法:选择50- 65岁的中老年人志愿者,排除有心、肝、肾及内分泌系统等严重疾患者,在试验开始前进行基线调查。将研究对象分为对照组和试验组,试验组服用复合营养素片,对照组服用安慰剂。试验开始和结束时分别测量体格指标、血液生化和免疫指标。结果:研究对象试验前,身高、体重和营养素摄入、血液生化指标和免疫指标两组均无差异(P>0．05)。6个月后,补充复合营养素的实验组血清维生素A、血清锌和全血硒高于对照组,差异有显著性(P<0．05);实验组的体液免疫指标血清IgA、IgG、IgM、补体c3高于对照组(P<0.05),所测定的细胞免疫指标两组无差别(P>0．05)。结论:提示该复合营养素补充剂能改善中老年人维生素A、锌、硒营养状况,并能促进体液免疫功能。更多还原

【Abstract】 Objective: To explore the impact of nutrients compound supplementation on nutritional and immune status in a middle-aged and elderly population. Methods: The volunteers aged 50-65 years old were randomized into two groups. The supplement was given to the experimental group, the control group took placebo. Results: The results showed that in comparison with the control group, the experimental group had a higher level of serum vitamin A and zinc, blood selenium. The humoral immune indices as IgA、IgG、IgM、 C3 of the experimental group were higher than that of the control group, but no significant difference of cellular immunity indices between two groups. Conclusion: The results indicated that the supplementation of this nutrients compound could improve the nutritional status of vitamin A, zinc and selenium, and may promote humoral immunity.更多还原