【作者】 董全进； 屠世良； 邓高里； 邹寿椿； 陈永伟； 徐慧英； 郑伯安； 赵仲生；

【Author】 Zhejiang Provincial People’ Hospital 310014 Dong Quanjin, Tu Shiliang, Deng Gaoli.et al.

【机构】 浙江省人民医院；

【摘要】 目的:探讨术前介入插管化疗在治疗中、低位直肠癌中的价值。方法: 术前化疗组:对60例中、低位直肠癌患者行术前介入插管化疗,7～10天后手术治疗,切除标本行病理组织学疗效观察;单纯手术组:对36例中、低位直肠癌行单纯手术治疗。并对两组结果进行总结分析。结果:术前介入插管化疗有效率100％。两组无围手术期死亡,无骶前出血,术前化疗组保肛率93．3％(56／60), 单纯手术组保肛率75．0％(27／36)。随访8-72个月,1年生存率分别为96．82％, 96．85％,3年生存率分别为83．77％,77．17％,5年生存率分别为62．55％,53．54％。结论:术前介入插管化疗可提高手术保肛率及5年生存率。更多还原

【Abstract】 Objective:To investigate the clinical values of preoperative aterial infusion chemotherapy in treating middle and low rectal cancer. Methods: Preoperative aterial infusion chemotherapy group:60 patients with middle or low rectal cancer were subjected to percutaneous femoral artery catheterization with infusion of anti-cancer drugs. The resection was performed 7-10 days after the arteriel infusion. After operation, the histological response was evaluated. Only operation group:36 patients with middle or low rectal cancer were only subjected to operation. The outcome of two groups were analysised. Results:In the two groups, There was no peri-operation death,no presacral hemorrhoid.The anus preserving rate were 93.3%,75.0%, respectively. The followed-up period were 8-72 months. The survival rate of 1,3,5 years were 96.82%/96.85%,83.77%/77.17%,62. 55%/53. 54%, respectively. Conclusion: Preoperative aterial infusion chemotherapy can improve the radical operation rate ,anus preserving rate, increase the long-term survival rate.更多还原