【作者】 周云芳； 陈志思； 吴素琴；

【Author】 ZHOU Yun- fang CHEN Zhi -en, WU Su-qin Lishui Second People’s Hospital, Lishui Zhejiang 323000, China

【机构】 丽水市第二人民医院；

【摘要】 目的:评价文拉法辛与氟西汀治疗抑郁症的临床疗效和不良反应。方法:对81例抑郁症随机分为两组,分别给予文拉法辛与氟西汀治疗6周,采用汉密顿抑郁量表(HAMD),汉密顿焦虑量表(HAMA),评定疗效,用副反应量表(TESS)评定不良反应。结果:文拉法辛组有效率为90％, 不良反应少而轻,安全性好,与氟西汀组比较差异无显著性。结论:文拉法辛是一种安全有效的抗抑郁药。更多还原

【Abstract】 Objective: To comepare efficacy and side effects of venlafaxine and fluoxetine in the treatment of depression. Method: 81 patients with depression were randomly assigned into the treatment groups of venlafaxine or fluoxetine for 6 weeks. HAMD, HAMA, were adopted to evaluate the therapeutic response,. TESS was adopted to evaluate the adverse effect . Results: 90% of patients responded to venlafaxine. The adverse effects were less and mild, No significant difference was found between the two prounps. Conclusion: venlafaxine is an effective and safe antidepressant.更多还原