【作者】 张雪萍； 白学敏；

【Author】 Zhang Xueping, Bai Xuemin (Wenxhou Research Inxtitute of Medical Science; Wenzhou 325003,China)

【机构】 温州市医药科学研究所；

【摘要】 目的:研究复方南瓜粉对糖尿病小鼠肾脏的保护作用。方法:以四氧嘧啶法制病理模型, 用本方喂养50天后,测定空腹血糖、胰岛素水平、解剖肾脏、称重、送电镜室检验,观察肾脏病理改变等项指标,综合评价复方南瓜粉对肾脏的保护作用。结果:实验组能显著降低肾脏重量系数、胰岛素抵抗指数、提高胰岛素敏感性指数、减轻炎症、抑制肾小球毛细血管基质膜增厚。结论:复方南瓜粉能抑制糖尿病肾病的发生,对肾脏有积极的保护作用。更多还原

【Abstract】 Objective: Study on protected kidney of the compound pumpkin powder in diabetic rats. Methods: Pothoiogic model by alloxan in rats,then dissected kidneys, weighted, warked pathology at after 50 days. Results: The kidney weight of diabetic rats were decresed (P<0.01) , abatement inflammation,inhibition,hyperplasia of the glomerulus basilar membrane. Conclusion: It can inhibite diabetic nephritic syndrome.更多还原