解毒祛湿、益气养阴法治疗SARS的临床研究

【作者】 张允岭； 张晓梅； 金耀文； 杨祖福； 谭湘恒； 张英； 王梅英； 杨玉昆； 张扬； 刘晓苏； 王玉来； 金章安； 林谦； 刘文娜； 郭小强； 熊富华； 张长增； 潘淑丽； 马允明； 冯桂兰； 何丽萍； 何月辉； 李红艳； 郭全；

【机构】 北京中医药大学东方医院； 北京市丰台区南苑医院； 中国残联博爱医院； 北京市丰台区铁营医院； 北京市丰台区长辛店医院； 北京市丰台区蒲黄榆医院； 北京市丰台区卫生局； 北京市丰台医院；

【摘要】 目的：较为客观地评价中药1、2、3号方结合西药基础疗法治疗 SARS 的临床疗效。方法：采用中国疾病预防控制中心公布的 SARS 诊断标准,制订纳入和排除标准。选取 63例临床确诊 SARS 病人,按病情轻重程度,分为普通症和重症,将普通症和重症分别随机分组．其中中西医结合组31例,单纯西药组32例,并根据 SARS 的自然进程和临床特征分为高热、喘憋、吸收三期。中西医结合组在西药基础治疗的同时,按证、期不同分别口服非典1、2、3号方,单纯西药组用西药基础治疗。选取发热所致的全身中毒症状与体征、X 线胸片、血常规及血生化等指标进行21天治疗观察。结果：中西医结合组可以明显减轻发烧所致的全身中毒症状,并且具有促进肺部炎症吸收的作用,与单纯西药组比较有显著性差异。结论：中西医结合治疗 SARS 取得临床疗效,无明显副作用。更多还原

【Abstract】 The objective was to evaluate the clinical curative effects of Traditional Chinese medicine (TCM) regimens 1,2 and 3 integrated with basic Western medicine in treatment of severe acute respiratory syndrome (SARS).In line with the diagnostic criteria for SARS issued by the Chinese Centre for Disease Control and Pre- vention,criteria for inclusion and exclusion of cases were decided upon.Sixty-three patients with clinically con- firmed SARS were selected and divided into normal cases and serious cases according to the severity of their illness, and were randomly assigned either to the integrated treatment group (31 eases) or the group treated with Western medicine (32 cases).The course of the illness was divided into three stages in accordance with the natural progres- sion and clinical manifestations of SARS (namely,the high fever stage,the dyspnoea and cough stage,and the ab- sorption stage).In the integrated treatment group,in addition to standard treatment,patients were instructed to take oral preparations of SARS regimens 1,2 or 3,for the high fever stage,the dyspnoea and cough stage,and the absorption stage,respectively.Patients in the group treated with Western medicine received standard treatment. Monitoring of general symptoms and signs caused by fever,chest X-ray films,the results of routine blood examina- tions and blood biochemical tests,and other indicators was carried out for 21 days.Therapy with the integrated treatment can obviously Alleviate general toxic symptoms and promote absorption of pulmonary inflammation;when compared with the effects in the group treated with Western medicine alone the differences were significant.Clinical curative effects were achieved through the administration of integrated TCM and Western medicine and no obvious side-effects were observed.更多还原