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表里经穴电针时的脑葡萄糖代谢PET对照研究

PET Comparison Study of interior-exterior Meridianpoints by Electroacupuncture Modulating Cerebral Glucose Metabolism

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【作者】 李霁左传涛董竞成乐晶晶

【机构】 复旦大学医学院附属华山医院

【摘要】 目的了解针刺表里特定经穴(解剖位置相对)对脑功能区影响的位置及其效应差异。方法表里经穴为手少阳三焦经的外关和支沟(10例),手厥阴心包经的内关和间使(12例),随机选单侧取穴。空白对照(5例)用正电子发射型计算机断层显像(PET)技术观察电针后局部脑葡萄糖代谢变化,。结果针刺表经穴位后,可见两侧中额叶和颞叶、丘脑、对侧小脑、海马等葡萄糖代谢增高变化(以对侧为主)。针刺里经穴位后,可见两侧中额叶,对侧颞叶、丘脑、小脑葡萄糖代谢减低变化和同侧海马、尾状核葡萄糖代谢增高变化。对照组没有变化。结论在生理状态下,针刺表里经穴对大脑起不同的调节作用。说明了穴位电针与脑功能区活动存在一定联系。

【Abstract】 Objective To explore the different effect of cerebral functional regions and the affected position by using electroacupuncture at specific interior-exterior meridian points (two acupoints are opposite to each other in their anatomic location) in healthy volunteers.Methods 27 subjects were randomly divided into 3 groups,10 subjects in the exterior meridian (Sanjiao) group treated by needling at SJ5 and SJ6,12 subjects in the interior meridian (Pericardium) group treated by needling at PC6 and PC5,and the rest 5 in blank group to compare to observe regional cerebral glucose metabolism change after electroacupuncture.All the needling was conducted at one side of upper limb. Results The cerebral glucose metabolism was elevated in bilateral mid-frontal lobe,temporal lobe,thalamus,and in contralateral cerebellum and hippocampus etc.;after acupuncturing at exterior meridian,The cerebral glucose metabolism was lowered in bilateral mid-frontal lobe,contralateral temporal lobe,thalamus and cerebellum after acupuncturing at interior meridian,while elevated in homolateral hippocampus and caudate nucleus.The cerebral glucose metabolism was not changed in blank group.Conclusion Under physiological condition,the regulatory effects on brain would be different as needling at interior-exterior meridian points and deduced to the specific relation of points electroacupuncture and cerebral functional regions.

  • 【会议录名称】 第十三届针灸对机体功能的调节机制及针灸临床独特经验学术研讨会暨第三届经络分会委员会会议论文集
  • 【会议名称】第十三届针灸对机体功能的调节机制及针灸临床独特经验学术研讨会暨第三届经络分会委员会会议
  • 【会议时间】2008-09
  • 【会议地点】中国福建厦门
  • 【分类号】R245
  • 【主办单位】中国针灸学会实验针灸分会、中国针灸学会经络分会、上海中医药大学附属岳阳中西医结合医院、上海市针灸经络研究所、《上海针灸杂志》编辑部
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