【作者】 张泓； 严洁； 易受乡； 常小荣； 刘玉群； 林亚平；

【Author】 ZHANG Hong, YAN Jie, YI Shou - xiang, CHANG Xiao - rong, LIU Yu - qun, LIN Ya - ping (Department of Acupuncture and Moxibustion, Hunan College of Traditional Chinese Medicine, Changsha, 410007,China)

【机构】 湖南中医学院针灸推拿系；

【摘要】 目的:通过电针足三阳经穴对家兔Oddi括约肌肌电发放及其相关脑肠肽胆囊收缩素(cholecystokinin,CCK)含量的影响,探讨针刺对Oddi括约肌的调整作用。方法:将60只家兔随机分为空白组(生理盐水组)、阿托品组、足三里组、阳陵泉组、四白组、承筋组。各组用生理记录仪记录Oddi括约肌肌电活动1h后,除空白组外,其余各组均静滴阿托品,静滴的同时足三里、阳陵泉、四白、承筋组分别电针相应腧穴20min。处理完成后重复记录Oddi肌肌电1h,放射免疫法检测血浆及Oddi括约肌组织内CCK的含量。结果:与阿托品组比较:①空白组、四白、足三里、阳陵泉组慢波高活动相及快波平均振幅明显升高。②电针四白、足三里、阳陵泉三穴均能使Oddi括约肌组织及血浆中CCK的含量升高;③在产生上调效应的三穴中,四白效应最佳、阳陵泉次之、足三里再次之。结论:①经(穴)对脏腑的调控作用存在相对特异性。②CCK是针刺对胆道系统运动起调节作用的重要脑肠肽之一;③生理、病理上有密切联系的脏腑之间,其所辖的经(穴)对这些脏腑还存在着或直接或间接的调控作用。更多还原

【Abstract】 Objective To explore the effect of electroacupuncture (EA) at three Foot Yang Meridians on rabbit oddi’ s sphincter movement and related brain - gut peptide content. Methods 60 rabbits were randomly divided into blank group, atropine group, Zusanli group, Yanglingquan group, Sibai group and Chengjin group. Physiology recorder used to record Oddi’s sphincter movement, 1 hour later, excepting blank group, rabbits in other groups were administrated by intravenous drip with atropine, meanwhile with EA at acupoints respectively for 20 minutes. Then Oddi’s sphincter movement was being recorded again for 1 hour. After the experiment, the contents of cholecystokinin (CCK) in plasma and Oddi’s sphincter were measured by radioimmunology. Results (1) Compared to atropine group, high movement phase of slow wave and average amplitude of fast wave rose in blank group, Sibai group, Zusanli group and Yanglingquan group. (2) EA at Sibai, Zusanli, Yanglingquan increased CCK contents of plasma and Oddi’ s sphincter.(3) As for the up - regulating effect for EA acupoints, Sibai was best, followed by Yanglingquan and Zusanli. Conclusion (1) The effect of meridian or acupoints regulating and controlling viscera is relatively specific. (2) CCK is one of important brain - gut peptides which could regulate gallbladder movement induced by acupuncture. (3) Meridians could regulate viscera function directly or indirectly.更多还原