多种中药动脉灌注治疗转移性肝癌的临床研究

【作者】 张青； 迟惠昌； 王笑民； 杨国旺； 赵文硕；

【机构】 北京中医医院肿瘤科；

【摘要】 目的:观察多种中药(康莱特、榄香烯、华蟾素)动脉灌注治疗转移性肝癌的疗效。方法:102例转移性肝襄患者,随机分治疗组(中药动脉灌注)52例、对照组(化学药物动脉灌注)50 例。结果:治疗组的有效率(CR+PR+MR)为50．0％,临床获益率(CR+PR+MR+SD)为73．1％,与对照组比较无显著性差异:而1年、2年生存率为67．3％、32．6％,明显高于对照组。多种中药动脉灌注既能保护患者的肝脏功能、提高患者的细胞免疫功能、改善患者的生活质量,还无明显的毒副作用。结论:中药多药动脉灌注治疗转移性肝癌疗效肯定,为中医药治疗恶性肿瘤提供了新的思路和方法。更多还原

【Abstract】 Objectives: To observe effect of combined traditional Chinese medicine drugs (Konlate,Elemene,Huachansu,)administrated intra-arterially in treatment of patients with metastatic liver cancer. Method: 102 patients with metastatic liver cancer were randomly assigned to treatment group(traditional Chinese medicine drugs administrated intra-arterially) with 52 patients and control group (chemotherapeutic agents administrated intra-arterially)with 50 patients. Results: Response rate(CR+PR+MR) of treatment group was 50.0%, rate of CR+PR+MR+SD was 32.6%which were significantly higher than control group. Combined traditional Chinese medicine drugs administrated intra-arterally had function of protecting liver function, improving cellular immune function of patients and improving quality of life of patients with no apparent adverse effects. Conclusion: Combined traditional Chinese medicine drugs administrated intra-arterially was effective in treatment of metastatic liver cancer. Our research provided new ways in treating malignant tumors with traditional Chinese medicine.更多还原