【作者】 滕荣伟； 王德祖； 杨崇仁；

【Author】 Rongwei Teng, Dezu Wang, Congren Yang (Kunming Institute of Botany, CAS, Kuming, 650204, e-mail: tengrongwei@hotmail.com)

【机构】 中国科学院昆明植物研究所；

【摘要】 从著名藏药白花刺参Morina nepalensis var.alba Hand.-Mazz.水溶性部分分离得到两个新坡摸醇酸三萜皂苷,刺参苷A(1)和刺参苷B(2)。应用了2D NMR新技术,包括GS DQF H-H COSY、GSHSQC、GSHMBC、2D HMQC-TOCSY、GSROESY以及选择性激发实验1D GS SELTOCSY和1D GOESY技术,并结合化学方法,鉴定了它们的结构分别为3-O-α-L-阿拉伯吡喃糖基-(1→3)-α-L-阿拉伯吡喃糖基坡摸醇酸28-O-β-D-葡萄吡喃糖基-(1→6)-β-D-葡萄吡喃糖苷(1)和3-O-α-L-阿拉伯吡喃糖基-(1→3)-β-D-木糖吡喃糖基坡摸醇酸28-O-β-D-葡萄吡喃糖基-(1→6)-β-D-葡萄吡喃糖苷(2),并对其氢和碳的化学位移进行了全归属。更多还原

【Abstract】 From water-soluble part of famous Tibetan medicinal herb, Marina nepalensis var. alba Hand. -Mazz., two new ursolic saponins, monepaloside A (1) and monepaloside B (2) were isolated. On the basis of spectroscopic and chemical evidences, their structures were elucidated as 3-O-α-L-arabinopyranosyl- (1-3) -α-L-arabinopyranosyl pomolic acid 28-O-β-D-glucopyranosyl- (1→6) -β-D-glucopyranoside and 3-O-α-L-arabinopyranosyl- ( 1→3 ) -β-D-xylopyranosyl pomolic acid 28-O-β-D-glucopyranosyl- (1→6 ) -β-D-glucopyranoside, repectively. 2D NMR techniques, including GS DQF H-H COSY、GSHSQC、GSHMBC、2D HMQC-TOCSY、GSROESYand ID GS SELTOCSY、1D GOESY, were utilized in the structure elucidation and complete assignments of NMR proton and carbon signals.更多还原