【作者】 叶远兰； 魏凤梅； 李玉谷； 张媛； 马勇江； 李楚宣； 邓衔柏； 江青艳；

【Author】 Ye Yuanlan~(1,2) Wei Fengmei~1 Li Yugu~1 Zhang Yuan~1 Ma Yongjiang~1 Li Chuxuan~1 Deng Xianbo~1 Jiang Qingyan~1 (1 College of Veterinary Medicine,South China Agriculture University,Guangzhou 510642,China; 2 Zhong Kai University of Agriculture and Engineering)

【机构】 华南农业大学兽医学院； 仲恺农业工程学院；

【摘要】 Ghrelin是生长激素促泌素受体的内源性配体,具有调节GH释放、调节摄食行为、调节能量平衡等功能。本试验运用免疫组织化学等方法,探讨了岭南黄羽肉鸡自由采食30d后分别禁食12h、24h、48h及其重新采食4h对下丘脑Ghrelin阳性神经元的影响。结果表明,在禁食条件下,下丘脑Ghrelin阳性神经元的免疫反应和细胞密度均下降,抑制Ghrelin的分泌。更多还原

【Abstract】 Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor(GHSR),and it regulates growth hormone release,influences feeding behavior,energy balance etc.In this paper,the effects of fasting 12h,24h,48h and refeeding 4h in 30-day-old broiler chickens on the ghrelin expressing cells in major nucleus of hypothalamus were studied by immunohistochemical method.The results showed that with the fasting and refeeding,the level of the ghrelin immunopositive reaction and the densities of ghrelin-immunopositive cells in the major nucleus of hypothalamus were decreased,fasting and refeeding inhibit the ghrelin secretion.更多还原