【作者】 李秀云； 刘果； 潘家鸣； 张寰波； 董玉光； 崔尚金； 李媛；

【Author】 Lixiuyun Liuguo Panjiaming Zhanghuanbo Dongyuguang(ChangChun Husbandry Prevention Centre Station)

【机构】 长春市畜禽防疫工作总站； 哈尔滨兽医研究所；

【摘要】 近年来,在新城疫La Sota疫苗免疫鸡群中不断有新城疫的发生(包括高抗体鸡群),有学者报道,其原因不仅与免疫方法、途径、疫苗等有关.更重要的是与新城疫毒株的变异.不同基因型的出现有关。用SPF鸡胚在吉林省患病鸡群中分离到一株病毒,经病毒形态学、结构特征、生物学、血清学及致病性等试验研究,确定该病毒为鸡新城疫强毒.致病性与鸡新城疫标准强毒F48E9差异显著.La Sota疫苗对该株病毒免疫保护效果不理想。更多还原

【Abstract】 In recent years, occurrence ND continuously occur in La Sota vaccine immunitzed chickens wLth high antibody level . Some scholars reported it related with not only method, route and vaccines etc. , but al.so variation in virulence and genotypes. One virus isolate was obtained from the diseased chicken flocks in JiIIIin province using SPF chicken embryos. By morphologic examination, structure and biological characterizatio n, serological tests and pathology study, this virus was identified as the ND high virulent strain, whose patholo gy characteristics were appeared different from those of the standard virulence NDV. La Sota vaccine could mot give good protection against the infection of this isolate.更多还原