Hypothalamic aromatization involves in electroacupuncture enhancing hypofunction of hypothalamus-pituitary-ovary axis in ovariectomized rats

【作者】 赵宏； 陈伯英；

【机构】 复旦大学上海医学院；

【摘要】 <正>Aromatase is the key enzyme responsible for estrogen biosynthesis. Considerable emphasis has been placed on the role of extragonadal aromatization in specific brain areas, which includes the anteroventral periventricular nucleus (AVPv), the medial basal hypothalamus and the suprachiasmatic-preoptic area. The total amount of estrogen synthesized in these areas may be small, but the local tissue concentrations achieved are high enough to exert significant biological influence locally, and principally, in a paracrine更多还原