【作者】 吴怀安； 沈其杰； 邓小敏； 胡赤怡；

【Author】 Huaian Shen Qijie Deng Xiaomin ZhangJun Hu Chiyi Shenzhen Institute of Mental Health Shenzhne518003P.R.China

【机构】 深圳市精神卫生研究所；

【摘要】 目的:搜寻21号染色体情感障碍易感性基因,探讨 D21s65多态性与情感障碍的关系。方法:应用微卫星 DNA 的二核苷酸串联重复序列多态性方法分析 D21s65与 AD 之间关系。结果:没有发现 AD 与 D21s65关联的证据。结论:本研究结果提示21q22.1区域不存在 AD 易感性基因。更多还原

【Abstract】 Objective:Search for gene predisposing to Affective disorder on chromosome 21.Tostudy the relationship between D21s65 Polymorphism length and Affective disorder.Method:To analy-sis the relationship between D21s65 Polymorphism length and Affective disorder using the dinucleotiderepet of microsatellite DNA methods.Results:This study demonstrated that the D21s65 marker is noassociation with Affective disorder of the Han nationality of Chinese.Conclusion:This results toints outthat the region of 21q22.1 is no a gene predisposing to Affective disorder in aur reaserch simples of theChinese.更多还原