【作者】 钱碧云； 陈可欣； 宋丰举； 李海欣； 何敏； 董淑芬； 雷蕾； 韩宏伟； 王培忠； 俞和；

【Author】 Qian Bi-Yun Chen Ke-Xin Song Feng-Ju Li Hai-Xin He Min Dong Shu-Fen Lei Lei Han Hong-Wei Wang Pei-Zhong Yu He Department of Cancer Epidemiology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

【机构】 天津医科大学附属肿瘤医院流行病室；

【摘要】 目的:对天津市居民1981-2000年间全人群恶性肿瘤的生存情况进行统计分析并了解其变化趋势,为评估 20年恶性肿瘤的防治效果提供依据。方法:将1981—2000年等分为四个时段,分性别统计1981-1985、1986-1990、 1991-1995和1996-2000年这四个时段全部恶性肿瘤的1 年、3年和5年生存率,并进行统计学检验,分析天津市20 年来全人群恶性肿瘤总体生存率变化趋势。结果:1981- 1985年间,天津城市居民全部恶性肿瘤1年、3年和5年总体生存率分别为43．92％、24．07％和19．81％,其中男性分别为37．95％,18．27％和14．39％;女性分别为50．87％、30． 82％和26．12％。1996—2000年间1年、3年和5年恶性肿瘤总体生存率分别为52．45％、39．37％和35．64％。其中男性分别为47．40％、33．41％和29．97％;女性分别为58．09％、 46．05％和42．02％o经Wilcoxon检验,从1981—1985、1986- 1990、1991-1995和1996—2000年间,四个时段总体生存率有显著差异(p<0．01),20年来天津市恶性肿瘤生存率呈逐渐升高趋势。5年生存率从1981-1985年的19．81％上升到 1996—2000年的35．64％,提高了约80％。男性膀胱癌、女性乳腺癌的5年生存率最高,1996—2000年分别达到 66．68％和81．16％。1981-1985年到1996—2000年全癌谱总体生存率的上升有6．25％是由于癌谱变化所致。结论:天津城市居民全人群恶性肿瘤5年总体生存率在20年期间明显大幅度提高,这与这段时期居民生活水平不断改善,癌谱发生变化有一定关系,但是人口寿命延长、肿瘤诊疗水平的不断提高以及早期发现、早期诊断率的提高起更加重要的作用。更多还原

【Abstract】 Objective: Cancer survival of all population-base in Tianjin city during 1981-2000 was analyzed in order to provide the evidence for cancer control and prevention among 20 years. Methods: The survival rate of cancer of 1-year, 3-year and 5-year was divided into four periods, 1981-1985,1986-1990,1991-1995,1996-2000 and calculated. The trend of survival rate with time was also compared. Results: The 1-year, 3-year and 5-year survival rate of cancer based population are 43.92%, 24.07% and 19.81% respectively; those are 37.95%,18.27% and 14.39% in male and 50.87%, 30.82% and 26.12% in female in 1981-1985. During 1996-2000, the survival rate are 52.45%, 39.37% and 35.64% respectively, those are 47.40%, 33.41 % and 29.97% in male and 58.09%, 46.05% and 42.02% in female. The Wilcoxon’ s test was used for the trend analysis and the result showed that the total survival rate has significant differences among the four periods (P<0.01). The survival rate of cancer indicated gradually increased trend with time in Tianjin among 20 years. The 5-year survival rate is elevated from 19.81 % in 1981-1985 to 35.64% in 1996-2000, increased about 80%. The survival rate of bladder cancer in male and breast cancer in female ranked highest, which are 66.68% and 81.16% respectively. 6.25% of the increase is from change of cancer spectrum recent 20 years. Conclusion: The 5-year total survival rate of cancer based population was elevated rapidly during 20 years. It is probably related with prolong of life expectancy, enhance of technique of diagnosis and treatment of cancer and improvement of the rate of early diagnosis expect for change of cancer spectrum due to the living level improvement.更多还原